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Human ovarian cancer stem/progenitor cells are stimulated by doxorubicin but inhibited by Mullerian inhibiting substance

Women with late-stage ovarian cancer usually develop chemotherapeutic-resistant recurrence. It has been theorized that a rare cancer stem cell, which is responsible for the growth and maintenance of the tumor, is also resistant to conventional chemotherapeutics. We have isolated from multiple ovaria...

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Autores principales: Meirelles, Katia, Benedict, Leo Andrew, Dombkowski, David, Pepin, David, Preffer, Frederic I., Teixeira, Jose, Tanwar, Pradeep Singh, Young, Robert H., MacLaughlin, David T., Donahoe, Patricia K., Wei, Xiaolong
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289387/
https://ncbi.nlm.nih.gov/pubmed/22308459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120733109
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