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Regulation of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) by reversible lysine acetylation

The enzyme inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) catalyzes the rate-limiting step in the formation of higher phosphorylated forms of inositol in mammalian cells. Because it sits at a key regulatory point in the inositol metabolic pathway, its activity is likely to be regulated. We have pre...

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Bibliographic Details
Main Authors: Zhang, Chunfen, Majerus, Philip W., Wilson, Monita P.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289378/
https://ncbi.nlm.nih.gov/pubmed/22308441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119740109
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