Transcriptional implications of ultradian glucocorticoid secretion in homeostasis and in the acute stress response

Endogenous glucocorticoids are secreted by the hypothalamic-pituitary-adrenal (HPA) axis in response to a wide range of stressors. Glucocorticoids exert significant downstream effects, including the regulation of many inflammatory genes. The HPA axis functions such that glucocorticoids are released...

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Hlavní autoři: Scheff, Jeremy D., Calvano, Steve E., Lowry, Stephen F., Androulakis, Ioannis P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
Call for Papers: Computational Modeling of Physiological Systems
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289115/
https://ncbi.nlm.nih.gov/pubmed/22128089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00128.2011
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