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Bayesian non-negative factor analysis for reconstructing transcription factor mediated regulatory networks

BACKGROUND: Transcriptional regulation by transcription factor (TF) controls the time and abundance of mRNA transcription. Due to the limitation of current proteomics technologies, large scale measurements of protein level activities of TFs is usually infeasible, making computational reconstruction...

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Autors principals: Meng, Jia, Zhang, Jianqiu (Michelle), Chen, Yidong, Huang, Yufei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289087/
https://ncbi.nlm.nih.gov/pubmed/22166063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-9-S1-S9
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