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Bayesian non-negative factor analysis for reconstructing transcription factor mediated regulatory networks

BACKGROUND: Transcriptional regulation by transcription factor (TF) controls the time and abundance of mRNA transcription. Due to the limitation of current proteomics technologies, large scale measurements of protein level activities of TFs is usually infeasible, making computational reconstruction...

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Hlavní autoři: Meng, Jia, Zhang, Jianqiu (Michelle), Chen, Yidong, Huang, Yufei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289087/
https://ncbi.nlm.nih.gov/pubmed/22166063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-9-S1-S9
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