Tissue factor pathway inhibitor blocks angiogenesis via its carboxyl terminus: Holroyd: TFPI regulates angiogenesis

OBJECTIVE: Tissue factor pathway inhibitor (TFPI) is the primary regulator of the tissue factor (TF) coagulation pathway. As such, TFPI may regulate the pro-angiogenic effects of TF. TFPI may also affect angiogenesis independently of TF, through sequences within its polybasic carboxyl terminus (TFPI...

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Auteurs principaux: Holroyd, Eric W., Chir, B., Delacroix, Sinny, Larsen, Katarina, Harbuzariu, Adriana, Psaltis, Peter J., Wang, Ling, Pan, Shuchong, White, Thomas A., Witt, Tyra A., Kleppe, Laurel S., Mueske, Cheryl S., Mukhopadhyay, Debabrata, Simari, Robert D.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288894/
https://ncbi.nlm.nih.gov/pubmed/22223730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.243733
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