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Reprogramming Urokinase into an Antibody-Recruiting Anticancer Agent

Synthetic compounds for controlling or creating human immunity have the potential to revolutionize disease treatment. Motivated by challenges in this arena, we report herein a strategy to target metastatic cancer cells for immune-mediated destruction by targeting the urokinase-type plasminogen activ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jakobsche, Charles E., McEnaney, Patrick J., Zhang, Andrew X., A. Spiegel, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288771/
https://ncbi.nlm.nih.gov/pubmed/22098560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200374e
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