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Spironolactone and colitis: Increased mortality in rodents and in humans
BACKGROUND AND METHODS: Crohn’s disease causes intestinal inflammation leading to intestinal fibrosis. Spironolactone is an anti-fibrotic medication commonly used in heart failure to reduce mortality. We examined whether spironolactone is anti-fibrotic in the context of intestinal inflammation. In v...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288762/ https://ncbi.nlm.nih.gov/pubmed/22081497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21929 |
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