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Adiponectin-AdipoR1/2-APPL1 Signaling Axis Suppresses Human Foam Cell Formation; Differential Ability of AdipoR1 and AdipoR2 to Regulate Inflammatory Cytokine Responses

OBJECTIVE: Adiponectin is an adipokine that exerts anti-inflammatory and anti-atherogenic effects during macrophage transformation into foam cells. To further understand the signaling pathways of adiponectin involved in macrophage foam cell transformation, we investigated the roles of two adiponecti...

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Autors principals: Tian, Ling, Luo, Nanlan, Zhu, Xiaolin, Chung, Byung-Hong, Garvey, W. Timothy, Fu, Yuchang
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288755/
https://ncbi.nlm.nih.gov/pubmed/22227293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2011.12.014
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