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Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts

The developing nervous system is particularly vulnerable to chemical insults. Exposure to chemicals can results in neurobehavioural alterations, and these have been be used as sensitive readouts to assess neurotoxicity in animals and man. Deconstructing neurobehaviour into relevant cellular and mole...

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Detalhes bibliográficos
Main Authors: van Thriel, Christoph, Westerink, Remco, Beste, Christian, Bale, Ambuja S., Lein, Pamela J., Leist, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288589/
https://ncbi.nlm.nih.gov/pubmed/22008243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2011.10.002
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