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EGFR signaling is required for regenerative proliferation in the cochlea: Conservation in birds and mammals

Proliferation and transdifferentiaton of supporting cells in the damaged auditory organ of birds leads to robust regeneration of sensory hair cells. In contrast, regeneration of lost auditory hair cells does not occur in deafened mammals, resulting in permanent hearing loss. In spite of this failure...

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Detalhes bibliográficos
Main Authors: White, Patricia M., Stone, Jennifer S., Groves, Andrew K., Segil, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288574/
https://ncbi.nlm.nih.gov/pubmed/22230616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.12.035
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