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Optical Imaging with HER2-targeted Affibody Molecules can monitor Hsp90 treatment response in a breast cancer xenograft mouse model

PURPOSE: To determine if optical imaging can be used for in vivo therapy response monitoring as an alternative to radionuclide techniques. For this we evaluated the known Her2 response to 17-DMAG treatment, a Hsp90 inhibitor. EXPERIMENTAL DESIGN: After in vitro 17-DMAG treatment response evaluation...

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Detalhes bibliográficos
Main Authors: van de Ven, Stephanie M.W.Y., Elias, Sjoerd G., Chan, Carmel T., Miao, Zheng, Cheng, Zhen, De, Abhijit, Gambhir, Sanjiv S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288571/
https://ncbi.nlm.nih.gov/pubmed/22235098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3213
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