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B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage

The Toll-like receptor adaptor protein MyD88 is essential for the regulation of intestinal homeostasis in mammals. In this study, we determined that Myd88-deficient mice are susceptible to colonic damage that is induced by dextran sulfate sodium (DSS) administration due to uncontrolled dissemination...

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Detalhes bibliográficos
Main Authors: Kirkland, Donna, Benson, Alicia, Mirpuri, Julie, Pifer, Reed, Hou, Baidong, DeFranco, Anthony L., Yarovinsky, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288553/
https://ncbi.nlm.nih.gov/pubmed/22306056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.11.019
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