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Induction of proinflammatory mediators by CHI3L1 is reduced by chitin treatment: decreased tumor metastasis in a breast cancer model

Disseminated metastasis accounts for over 90% of breast cancer deaths. Recently, elevated serum levels of a glycoprotein known as chitinase-3 like-protein-1 (CHI3L1) has been correlated with poor prognosis and shorter survival of patients with metastatic breast cancer. In this study, we show that th...

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Detalhes bibliográficos
Main Authors: Libreros, Stephania, Garcia-Areas, Ramon, Shibata, Yoshimi, Carrio, Roberto, Torroella-Kouri, Marta, Iragavarapu-Charyulu, Vijaya
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288379/
https://ncbi.nlm.nih.gov/pubmed/21866546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26379
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