Generating CTLs against the subdominant EBV LMP antigens by transit expression of an A20 inhibitor with EBV LMP proteins in human DCs

Epstein-Barr virus (EBV) infection leads to Hodgkin’s disease (HD) in some immunocompetent hosts. The malignant Reed-Sternberg cells of HD only express a limited array of subdominant EBV antigens to evade preexisting immune responses to EBV. The EBV-encoded latent membrane proteins (LMP1 and LMP2),...

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Bibliographic Details
Main Authors: Hong, Bangxing, Peng, Guangyong, Berry, Lindsey, Gottschalk, Stephen, Jung, Jae U, Chen, Si-Yi, Huang, Xue F
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288357/
https://ncbi.nlm.nih.gov/pubmed/22052242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.160
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