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Activation of the unfolded protein response enhances motor recovery after spinal cord injury

Spinal cord injury (SCI) is a major cause of paralysis, and involves multiple cellular and tissular responses including demyelination, inflammation, cell death and axonal degeneration. Recent evidence suggests that perturbation on the homeostasis of the endoplasmic reticulum (ER) is observed in diff...

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Detalhes bibliográficos
Principais autores: Valenzuela, V, Collyer, E, Armentano, D, Parsons, G B, Court, F A, Hetz, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288350/
https://ncbi.nlm.nih.gov/pubmed/22337234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.8
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