CLIPR-59 regulates TNF-α-induced apoptosis by controlling ubiquitination of RIP1

Tumor necrosis factor-α (TNF-α) has important roles in several immunological events by regulating apoptosis and transcriptional activation of cytokine genes. Intracellular signaling mediated by TNF-receptor-type 1 (TNFR1) is constituted by two sequential protein complexes: Complex-I containing the r...

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Bibliographic Details
Main Authors: Fujikura, D, Ito, M, Chiba, S, Harada, T, Perez, F, Reed, J C, Uede, T, Miyazaki, T
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288345/
https://ncbi.nlm.nih.gov/pubmed/22297296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.3
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