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Clinical relevance of Ephs and ephrins in cancer: lessons from breast, colorectal, and lung cancer profiling
Pre-clinical studies provide compelling evidence that members of the Eph family of receptor tyrosine kinases and their ephrin ligands promote tumor growth, invasion and metastasis, and neovascularization. Tumor suppressive roles have also been reported for the receptors, and ligand-dependent versus...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288332/ https://ncbi.nlm.nih.gov/pubmed/22040912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.10.014 |
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