Older patients with normal karyotype acute myeloid leukemia have a higher rate of genomic changes compared to young patients as determined by SNP array analysis

Older patients with AML have a worse outcome compared to young patients. To study for potential contributors to their poor prognosis, we compared two NK-AML cohorts, young (< 60 years old) and old (> 60 years old), via high density SNP array analysis. Older patients had more genomic changes (1...

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Main Authors: Koren-Michowitz, Maya, Sato-Otsubo, Aiko, Nagler, Arnon, Haferlach, Torsten, Ogawa, Seishi, Koeffler, H. Phillip
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288295/
https://ncbi.nlm.nih.gov/pubmed/22071139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2011.10.013
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