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Analgesia by inhibiting tetrahydobiopterin synthesis

Physiological control of the co-factor tetrahydrobiopterin (BH4) is tight in normal circumstances but levels increase pathologically in the injured somatosensory system. BH4 is an essential co-factor in the production of serotonin, dopamine, epinephrine, norepinephrine and nitric oxide. Excess BH4 l...

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Hlavní autoři: Costigan, Michael, Latremoliere, Alban, Woolf, Clifford J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288148/
https://ncbi.nlm.nih.gov/pubmed/22178186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2011.10.019
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