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Association between Sclerostin and Bone Density in Chronic SCI

Spinal cord injury (SCI) results in profound bone loss due to muscle paralysis and the inability to ambulate. Sclerostin, a Wnt signaling pathway antagonist produced by osteocytes, is a potent inhibitor of bone formation. Short-term studies in rodent models have demonstrated increased sclerostin in...

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Detalhes bibliográficos
Main Authors: Morse, Leslie R., Sudhakar, Supreetha, Danilack, Valery, Tun, Carlos, Lazzari, Antonio, Gagnon, David R., Garshick, Eric, Battaglino, Ricardo A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288145/
https://ncbi.nlm.nih.gov/pubmed/22006831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.546
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