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Association between Sclerostin and Bone Density in Chronic SCI
Spinal cord injury (SCI) results in profound bone loss due to muscle paralysis and the inability to ambulate. Sclerostin, a Wnt signaling pathway antagonist produced by osteocytes, is a potent inhibitor of bone formation. Short-term studies in rodent models have demonstrated increased sclerostin in...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288145/ https://ncbi.nlm.nih.gov/pubmed/22006831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.546 |
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