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E4F1 dysfunction results in autophagic cell death in myeloid leukemic cells

The multifunctional E4F1 protein was originally identified as a cellular target of the E1A adenoviral oncoprotein. Although E4F1 is implicated in several key oncogenic pathways, its roles in tumorigenesis remain unclear. Using a genetically engineered mouse model of myeloid leukemia (histiocytic sar...

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Bibliografiske detaljer
Main Authors: Hatchi, Elodie, Rodier, Geneviève, Sardet, Claude, Le Cam, Laurent
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288034/
https://ncbi.nlm.nih.gov/pubmed/22024746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.17991
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