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Activation of autophagy is required for muscle homeostasis during physical exercise
Skeletal muscle fibers of collagen VI null (Col6a1−/−) mice show signs of degeneration due to a block in autophagy, leading to the accumulation of damaged mitochondria and excessive apoptosis. Attempts to induce autophagic flux by subjecting these mutant mice to long-term or shorter bursts of physic...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288013/ https://ncbi.nlm.nih.gov/pubmed/22082869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.18315 |
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