Detecting disease rare alleles using single SNPs in families and haplotyping in unrelated subjects from the Genetic Analysis Workshop 17 data

We present an evaluation of discovery power for two association tests that work well with common alleles but are applied to the Genetic Analysis Workshop 17 simulations with rare causative single-nucleotide polymorphisms (SNPs) (minor allele frequency [MAF] < 1%). The methods used were genome-wid...

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Bibliographische Detailangaben
Hauptverfasser: Kraja, Aldi T, Czajkowski, Jacek, Feitosa, Mary F, Borecki, Ingrid B, Province, Michael A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Proceedings
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287938/
https://ncbi.nlm.nih.gov/pubmed/22373254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S96
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