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Prioritizing single-nucleotide variations that potentially regulate alternative splicing

Recent evidence suggests that many complex diseases are caused by genetic variations that play regulatory roles in controlling gene expression. Most genetic studies focus on nonsynonymous variations that can alter the amino acid composition of a protein and are therefore believed to have the highest...

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Autors principals: Teng, Mingxiang, Wang, Yadong, Wang, Guohua, Jung, Jeesun, Edenberg, Howard J, Sanford, Jeremy R, Liu, Yunlong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287877/
https://ncbi.nlm.nih.gov/pubmed/22373210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S40
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