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Identification of genes and variants associated with quantitative traits using Bayesian factor screening

We propose a factor-screening method based on a Bayesian model selection framework and apply it to Genetic Analysis Workshop 17 simulated data with unrelated individuals to identify genes and SNP variants associated with the quantitative trait Q1. A Metropolis-Hasting algorithm is implemented to gen...

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Détails bibliographiques
Auteurs principaux: Pradhan, Kith, Yoon, Seungtai Chris, Wang, Tao, Ye, Kenny
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287876/
https://ncbi.nlm.nih.gov/pubmed/22373183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S4
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