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Family- and population-based designs identify different rare causal variants

Both family- and population-based samples are used to identify genetic variants associated with phenotypes. Each strategy has demonstrated advantages, but their ability to identify rare variants and genes containing rare variants is unclear. To compare these two study designs in the identification o...

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Detalhes bibliográficos
Main Authors: Zhang, Xue, He, Hua, Ding, Lili, Baye, Tesfaye M, Kurowski, Brad G, Martin, Lisa J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287872/
https://ncbi.nlm.nih.gov/pubmed/22373077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S36
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