Purification of the DNA binding domain of herpes simplex virus type 1 immediate-early protein Vmw175 as a homodimer and extensive mutagenesis of its DNA recognition site.

The herpes simplex virus type 1 (HSV-1) Immediate-Early (IE) polypeptide Vmw175 is essential for the activation of transcription from viral early and late promoters. Vmw175 also reduces the activity of its own (IE-3) promoter in transfection assays. Both transactivation and repression mediated by Vm...

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Publicat a:Nucleic Acids Res
Autors principals: Everett, R D, Elliott, M, Hope, G, Orr, A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1991
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328787/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1656382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.18.4901
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