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Association screening for genes with multiple potentially rare variants: an inverse-probability weighted clustering approach

Both common variants and rare variants are involved in the etiology of most complex diseases in humans. Developments in sequencing technology have led to the identification of a high density of rare variant single-nucleotide polymorphisms (SNPs) on the genome, each of which affects only at most 1% o...

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Main Authors: Liu, Ying, Huang, Chien Hsun, Hu, Inchi, Lo, Shaw-Hwa, Zheng, Tian
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287829/
https://ncbi.nlm.nih.gov/pubmed/22373536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S106
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