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Detection of associations with rare and common SNPs for quantitative traits: a nonparametric Bayes-based approach

We propose a nonparametric Bayes-based clustering algorithm to detect associations with rare and common single-nucleotide polymorphisms (SNPs) for quantitative traits. Unlike current methods, our approach identifies associations with rare genetic variants at the variant level, not the gene level. In...

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Bibliografiske detaljer
Main Authors: Ding, Lili, Baye, Tesfaye M, He, Hua, Zhang, Xue, Kurowski, Brad G, Martin, Lisa J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287822/
https://ncbi.nlm.nih.gov/pubmed/22373351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S10
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