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A new protein-ligand binding sites prediction method based on the integration of protein sequence conservation information

BACKGROUND: Prediction of protein-ligand binding sites is an important issue for protein function annotation and structure-based drug design. Nowadays, although many computational methods for ligand-binding prediction have been developed, there is still a demanding to improve the prediction accuracy...

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Détails bibliographiques
Auteurs principaux: Dai, Tianli, Liu, Qi, Gao, Jun, Cao, Zhiwei, Zhu, Ruixin
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287474/
https://ncbi.nlm.nih.gov/pubmed/22373099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S14-S9
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