Correlation between LTR point mutations and proviral load levels among Human T cell Lymphotropic Virus type 1 (HTLV-1) asymptomatic carriers

BACKGROUND: In vitro studies have demonstrated that deletions and point mutations introduced into each 21 bp imperfect repeat of Tax-responsive element (TRE) of the genuine human T-cell leukemia virus type I (HTLV-1) viral promoter abolishes Tax induction. Given these data, we hypothesized that simi...

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Main Authors: Neto, Walter K, Da-Costa, Antonio C, de Oliveira, Ana Carolina S, Martinez, Vanessa P, Nukui, Youko, Sabino, Ester C, Sanabani, Sabri S
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287369/
https://ncbi.nlm.nih.gov/pubmed/22166003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-535
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