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Ultrasound-Enhanced Thrombolytic Effect of Tissue Plasminogen Activator–Loaded Echogenic Liposomes in an In Vivo Rabbit Aorta Thrombus Model—Brief Report

OBJECTIVE: Ultrasound enhances thrombolysis when combined with a thrombolytic and a contrast agent. This study aimed to evaluate the thrombolytic effect of our tissue plasminogen activator (tPA)–loaded echogenic liposomes (ELIP) in an in vivo clot model, with and without ultrasound treatment. METHOD...

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Detalles Bibliográficos
Main Authors: Laing, Susan T., Moody, Melanie, Smulevitz, Beverly, Kim, Hyunggun, Kee, Patrick, Huang, Shaoling, Holland, Christy K., McPherson, David D.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287366/
https://ncbi.nlm.nih.gov/pubmed/21441137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.225938
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