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Overnight ACTH-Cortisol Dose-Responsiveness: comparison with 24-hr data, metyrapone administration, and insulin-tolerance test in healthy adults

OBJECTIVE: To estimate the dose-dependence of endogenous ACTH’s stimulation of adrenal cortisol secretion overnight. DESIGN: Ten-minute sampling for ACTH and cortisol over 8 and 24 hr (N=17), after metyrapone administration (N=6), during an insulin tolerance test (N=7). SUBJECTS: Healthy adults. MEA...

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Bibliographic Details
Main Authors: Iranmanesh, Ali, Keenan, Daniel M., Aoun, Paul, Veldhuis, Johannes D.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287347/
https://ncbi.nlm.nih.gov/pubmed/21609353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2265.2011.04125.x
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