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Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes

The ability of mammals to resist body fat accumulation is linked to their ability to expand the number and activity of “brown adipocytes” within white fat depots. Activation of β-adrenergic receptors (β-ARs) can induce a functional “brown-like” adipocyte phenotype. As cardiac natriuretic peptides (N...

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Main Authors: Bordicchia, Marica, Liu, Dianxin, Amri, Ez-Zoubir, Ailhaud, Gerard, Dessì-Fulgheri, Paolo, Zhang, Chaoying, Takahashi, Nobuyuki, Sarzani, Riccardo, Collins, Sheila
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287224/
https://ncbi.nlm.nih.gov/pubmed/22307324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59701
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