Loading...

Macrophage plasticity and polarization: in vivo veritas

Diversity and plasticity are hallmarks of cells of the monocyte-macrophage lineage. In response to IFNs, Toll-like receptor engagement, or IL-4/IL-13 signaling, macrophages undergo M1 (classical) or M2 (alternative) activation, which represent extremes of a continuum in a universe of activation stat...

Full description

Saved in:
Bibliographic Details
Main Authors: Sica, Antonio, Mantovani, Alberto
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287223/
https://ncbi.nlm.nih.gov/pubmed/22378047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59643
Tags: Add Tag
No Tags, Be the first to tag this record!