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Macrophage plasticity and polarization: in vivo veritas

Diversity and plasticity are hallmarks of cells of the monocyte-macrophage lineage. In response to IFNs, Toll-like receptor engagement, or IL-4/IL-13 signaling, macrophages undergo M1 (classical) or M2 (alternative) activation, which represent extremes of a continuum in a universe of activation stat...

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Bibliografiske detaljer
Main Authors: Sica, Antonio, Mantovani, Alberto
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287223/
https://ncbi.nlm.nih.gov/pubmed/22378047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59643
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