Protective antifungal memory CD8(+) T cells are maintained in the absence of CD4(+) T cell help and cognate antigen in mice

Individuals who are immunocompromised, including AIDS patients with few CD4(+) T cells, are at increased risk for opportunistic fungal infections. The incidence of such infections is increasing worldwide, meaning that the need for antifungal vaccines is increasing. Although CD4(+) T cells play a dom...

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Bibliografiska uppgifter
Huvudupphovsmän: Nanjappa, Som G., Heninger, Erika, Wüthrich, Marcel, Sullivan, Thomas, Klein, Bruce
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287218/
https://ncbi.nlm.nih.gov/pubmed/22354169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58762
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