Interferon gamma (IFN-γ) disrupts energy expenditure and metabolic homeostasis by suppressing SIRT1 transcription

Chronic inflammation impairs metabolic homeostasis and is intimately correlated with the pathogenesis of type 2 diabetes. The pro-inflammatory cytokine IFN-γ is an integral part of the metabolic inflammation circuit and contributes significantly to metabolic dysfunction. The underlying mechanism, ho...

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Bibliographic Details
Main Authors: Li, Ping, Zhao, Yuhao, Wu, Xiaoyan, Xia, Minjie, Fang, Mingming, Iwasaki, Yasumasa, Sha, Jiahao, Chen, Qi, Xu, Yong, Shen, Aiguo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Gene Regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287208/
https://ncbi.nlm.nih.gov/pubmed/22064865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr984
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