Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion

Postprandial insulin release is regulated by glucose, but other circulating nutrients may target beta cells and potentiate glucose-stimulated insulin secretion via distinct signaling pathways. We demonstrate that fructose activates sweet taste receptors (TRs) on beta cells and synergizes with glucos...

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Hauptverfasser: Kyriazis, George A., Soundarapandian, Mangala M., Tyrberg, Björn
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286985/
https://ncbi.nlm.nih.gov/pubmed/22315413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115183109
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