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Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development

Dramatic changes in chromatin structure and histone modification occur during oocyte growth, as well as a global cessation of transcription. The role of histone modifications in these processes is poorly understood. We report the effect of conditionally deleting Hdac1 and Hdac2 on oocyte development...

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Detalhes bibliográficos
Main Authors: Ma, Pengpeng, Pan, Hua, Montgomery, Rusty L., Olson, Eric N., Schultz, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286984/
https://ncbi.nlm.nih.gov/pubmed/22223663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118403109
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