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Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses
Endocytic recycling of synaptic vesicles after exocytosis is critical for nervous system function. At synapses of cultured neurons that lack the two “neuronal” dynamins, dynamin 1 and 3, smaller excitatory postsynaptic currents are observed due to an impairment of the fission reaction of endocytosis...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286982/ https://ncbi.nlm.nih.gov/pubmed/22308498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121626109 |
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