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Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

Antiangiogenic therapy has been thought to hold significant potential for the treatment of cancer. However, the efficacy of such treatments, especially in breast cancer patients, has been called into question, as recent clinical trials reveal only limited effectiveness of antiangiogenic agents in pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Conley, Sarah J., Gheordunescu, Elizabeth, Kakarala, Pramod, Newman, Bryan, Korkaya, Hasan, Heath, Amber N., Clouthier, Shawn G., Wicha, Max S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286974/
https://ncbi.nlm.nih.gov/pubmed/22308314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018866109
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