The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway

Multiple factors including long-term treatment with tamoxifen are involved in the development of selective estrogen receptor (ER) modulator resistance in ERα-positive breast cancer. Many underlying molecular events that confer resistance are known but a unifying theme is yet to be revealed. In this...

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Detalhes bibliográficos
Main Authors: Jin, Kideok, Kong, Xiangjun, Shah, Tariq, Penet, Marie-France, Wildes, Flonne, Sgroi, Dennis C., Ma, Xiao-Jun, Huang, Yi, Kallioniemi, Anne, Landberg, Goran, Bieche, Ivan, Wu, Xinyan, Lobie, Peter E., Davidson, Nancy E., Bhujwalla, Zaver M., Zhu, Tao, Sukumar, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Breast Cancer Special Feature
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286915/
https://ncbi.nlm.nih.gov/pubmed/21690342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018859108
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