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Time-dependent Conformational Changes in Adsorbed Albumin and its Effect on Platelet Adhesion

Recent studies have shown that platelets can adhere to adsorbed albumin (Alb) through a receptor-mediated mechanism, but only if the Alb undergoes more than a critical degree of adsorption-induced unfolding. The objectives of this research were to investigate whether Alb that was initially adsorbed...

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Detalhes bibliográficos
Main Authors: Sivaraman, Balakrishnan, Latour, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286649/
https://ncbi.nlm.nih.gov/pubmed/22191731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la204777x
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