Preventing intimal thickening of vein grafts in vein artery bypass using STAT-3 siRNA

BACKGROUND: Proliferation and migration of vascular smooth muscle cells (VSMCs) play a key role in neointimal formation which leads to restenosis of vein graft in venous bypass. STAT-3 is a transcription factor associated with cell proliferation. We hypothesized that silencing of STAT-3 by siRNA wil...

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Autori principali: Sun, Jiangbin, Zheng, Jinhua, Ling, Kaitelynne H, Zhao, Keyan, Xie, Zhongshang, Li, Bo, Wang, Tiance, Zhu, Zhicheng, Patel, Amit N, Min, Weiping, Liu, Kexiang, Zheng, Xiufen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286375/
https://ncbi.nlm.nih.gov/pubmed/22216901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-2
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