Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by coculture with macrophage feeder cells

B-cell chronic lymphocytic leukemia (B-CLL) is characterized by the clonal expansion of CD5-expressing B lymphocytes that produce mAbs often reactive with microbial or autoantigens. Long-term culture of B-CLL clones would permit the collection and characterization of B-CLL mAbs to study antigen spec...

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Detalhes bibliográficos
Main Authors: Hwang, Kwan-Ki, Chen, Xi, Kozink, Daniel M., Gustilo, Marietta, Marshall, Dawn J., Whitesides, John F., Liao, Hua-Xin, Catera, Rosa, Chu, Charles C., Yan, Xiao-Jie, Luftig, Micah A., Haynes, Barton F., Chiorazzi, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286354/
https://ncbi.nlm.nih.gov/pubmed/22160618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-371203
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