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Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) deficient mice have an altered immune cell phenotype
Cross-linking of the collagen binding receptor LAIR-1 in vitro delivers an inhibitory signal that is able to down-regulate activation-mediated signals. To study the in vivo function of LAIR-1, we generated LAIR-1(−/−) mice. They are healthy and fertile, and have normal longevity; however, they show...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286132/ https://ncbi.nlm.nih.gov/pubmed/22156345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102044 |
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