Conditionally Immortalized Mouse Embryonic Fibroblasts Retain Proliferative Activity without Compromising Multipotent Differentiation Potential

Mesenchymal stem cells (MSCs) are multipotent cells which reside in many tissues and can give rise to multiple lineages including bone, cartilage and adipose. Although MSCs have attracted significant attention for basic and translational research, primary MSCs have limited life span in culture which...

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Main Authors: Huang, Enyi, Bi, Yang, Jiang, Wei, Luo, Xiaoji, Yang, Ke, Gao, Jian-Li, Gao, Yanhong, Luo, Qing, Shi, Qiong, Kim, Stephanie H., Liu, Xing, Li, Mi, Hu, Ning, Liu, Hong, Cui, Jing, Zhang, Wenwen, Li, Ruidong, Chen, Xiang, Shen, Jikun, Kong, Yuhan, Zhang, Jiye, Wang, Jinhua, Luo, Jinyong, He, Bai-Cheng, Wang, Huicong, Reid, Russell R., Luu, Hue H., Haydon, Rex C., Yang, Li, He, Tong-Chuan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285668/
https://ncbi.nlm.nih.gov/pubmed/22384246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032428
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