Genetic Polymorphisms of the TYMS Gene Are Not Associated with Congenital Cardiac Septal Defects in a Han Chinese Population

BACKGROUND: Clinical research indicates that periconceptional administration of folic acid can reduce the occurrence of congenital cardiac septal defects (CCSDs). The vital roles of folate exhibits in three ways: the unique methyl donor for DNA expression regulation, the de novo biosynthesis of puri...

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Hlavní autoři: Zhao, Jian-Yuan, Sun, Jing-Wei, Gu, Zhuo-Ya, Wang, Jue, Wang, Er-Li, Yang, Xue-Yan, Qiao, Bin, Duan, Wen-Yuan, Huang, Guo-Ying, Wang, Hong-Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285645/
https://ncbi.nlm.nih.gov/pubmed/22384047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031644
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