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Molecular diagnosis of sex chromosome aneuploidy using quantitative PCR.
Numeric sex chromosome imbalances, or aneuploidies, are present in several pathological conditions including tumors, abnormal gestations, and clinical syndromes. Here we report a method to identify karyotypic imbalances of the X and Y chromosomes using the polymerase chain reaction (PCR). The polyme...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1991
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC328563/ https://ncbi.nlm.nih.gov/pubmed/1678507 |
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