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A Bistable Model of Cell Polarity

Ultrasensitivity, as described by Goldbeter and Koshland, has been considered for a long time as a way to realize bistable switches in biological systems. It is not as well recognized that when ultrasensitivity and reinforcing feedback loops are present in a spatially distributed system such as the...

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Autori principali: Semplice, Matteo, Veglio, Andrea, Naldi, Giovanni, Serini, Guido, Gamba, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285628/
https://ncbi.nlm.nih.gov/pubmed/22383986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030977
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